2002-2003 Biomedical Engineering

Interdepartmental Program

Upper Division Courses

C101. Introduction to Biomedical Engineering. (4) (Formerly numbered 101.) Lecture, three hours; laboratory, three hours; outside study, six hours. Designed for physical sciences, life sciences, and engineering students. Introduction to wide scope of biomedical engineering via treatment of selected important individual topics by small team of specialists. Concurrently scheduled with course C201. Letter grading. Mr. Kabo (F)

CM102. Human Anatomy for Biomedical Engineers. (4) (Formerly numbered M102.) (Same as Physiological Science CM102.) Lecture, three hours; laboratory, two hours. Not open for credit to Physiological Science majors. Designed to provide foundation in human gross and microscopic anatomy for graduate biomedical engineering students. Broad overview of structural organization of human body and detailed examination of specific systems pertinent to biomedical research. Concurrently scheduled with course CM202. Letter grading. Mr. Montemagno (F)

CM103. Human Physiology for Biomedical Engineers. (4) (Formerly numbered M103.) (Same as Physiological Science CM103.) Lecture, three hours; laboratory, two hours. Not open for credit to Physiological Science majors. Designed to provide foundation in human physiology for graduate biomedical engineering students. Systematic approach to examination of major systems function, with emphasis on regulatory mechanisms controlling normal function. Detailed examination of specific systems pertinent to major areas of biomedical research. Concurrently scheduled with course CM203. Letter grading. Mr. Montemagno (W)

CM140. Introduction to Biomechanics. (4) (Formerly numbered M140.) (Same as Mechanical and Aerospace Engineering CM140.) Lecture, four hours; outside study, eight hours. Requisites: Mechanical and Aerospace Engineering 102 (or Civil Engineering 108), 156A. Introduction to mechanical functions of human body; skeletal adaptations to optimize load transfer, mobility, and function. Dynamics and kinematics. Fluid mechanics applications. Heat and mass transfer. Power generation. Laboratory simulations and tests. Concurrently scheduled with course CM240. Letter grading. Mr. Gupta (W)

C141L. Biomechanics Laboratory. (4) Lecture, one hour; laboratory, three hours; outside study, eight hours. Requisite: course CM140 or Mechanical and Aerospace Engineering 156A. Hands-on laboratory pertaining to mechanical testing and analysis of long bone specimens. Students, working in pairs, engage in all aspects of procedures. Fundamentals include design and fabrication of signal processing circuitry for use in data acquisition process, including bridge completion circuits, amplifiers, and passive filters; computerized data acquisition using Lab View and A/D input/output (I/O) board; strain measurements on metallic and bone specimens. Finite element analysis of structure under investigation; comparison of experimental, theoretical, and computational results. Concurrently scheduled with course C241L. Letter grading.

CM145. Molecular Biotechnology for Engineers. (4) (Same as Chemical Engineering CM145.) Lecture, four hours; discussion, one hour; outside study, eight hours. Selected topics in molecular biology that form foundation of biotechnology and biomedical industry today. Topics include recombinant DNA technology, molecular research tools, manipulation of gene expression, directed mutagenesis and protein engineering, DNA-based diagnostics and DNA microarrays, antibody and protein-based diagnostics, genomics and bioinformatics, isolation of human genes, gene therapy, and tissue engineering. Concurrently scheduled with course CM245. Letter grading. Mr. Liao (F)

M150L. Introduction to Micromachining and Microelectromechanical Systems Laboratory. (4) (Same as Electrical Engineering M150L and Mechanical and Aerospace Engineering M180L.) Lecture, three hours; laboratory, four hours; outside study, five hours. Requisites: Electrical Engineering 1 or Physics 1C, Chemistry 20A. Introduction to micromachining technologies and microelectromechanical systems (MEMS). Methods of micromachining and how these methods can be used to produce a variety of MEMS, including microstructures, microsensors, and microactuators. Students fabricate set of basic MEMS structures in hands-on microfabrication laboratory. Letter grading. Mr. Judy (F)

C170. Energy-Tissue Interactions. (4) Lecture, three hours; outside study, nine hours. Requisites: Electrical Engineering 172, 175, Life Sciences 3, Physics 17. Corequisite: course C170L. Introduction to therapeutic and diagnostic use of energy delivery devices in medical and dental applications, with emphasis on understanding fundamental mechanisms underlying various types of energy-tissue interactions. Concurrently scheduled with course C270. Letter grading. Mr. Grundfest (F)

C170L. Introduction to Techniques in Studying Laser-Tissue Interaction. (2) Laboratory, four hours; outside study, two hours. Corequisite: course C170. Introduction to simulation and experimental techniques used in studying laser-tissue interactions. Topics include computer simulations of light propagation in tissue, measuring absorption spectra of tissue/tissue phantoms, making tissue phantoms, determination of optical properties of different tissues, techniques of temperature distribution measurements. Concurrently scheduled with course C270L. Letter grading.

C171. Laser-Tissue Interaction II: Biologic Spectroscopy. (4) Lecture, four hours; outside study, eight hours. Requisite: course C170. Designed for physical sciences, life sciences, and engineering majors. Introduction to optical spectroscopy principles, design of spectroscopic measurement devices, optical properties of tissues, and fluorescence spectroscopy biologic media. Concurrently scheduled with course C271. Letter grading. Mr. Grundfest (W)

CM180. Introduction to Biomaterials. (4) (Formerly numbered M180.) (Same as Materials Science CM180.) Lecture, three hours; discussion, two hours; outside study, seven hours. Requisites: Chemistry 20A, 20B, and 20L, or Materials Science 14. Engineering materials used in medicine and dentistry for repair and/or restoration of damaged natural tissues. Topics include relationships between material properties, suitability to task, surface chemistry, processing and treatment methods, and biocompatibility. Concurrently scheduled with course CM280. Letter grading. Mr. Wu (W)

C181. Biomaterials-Tissue Interactions. (4) Lecture, three hours; outside study, nine hours. Requisite: course CM180. In-depth exploration of host cellular response to biomaterials: vascular response, interface, and clotting, biocompatibility, animal models, inflammation, infection, extracellular matrix, cell adhesion, and role of mechanical forces. Concurrently scheduled with course C281. Letter grading. Mr. Wu (Sp)

C185. Introduction to Tissue Engineering. (4) Lecture, three hours; outside study, nine hours. Requisites: course CM102 or CM202, Chemistry 20A, 20B, 20L. Tissue engineering applies principles of biology and physical sciences with engineering approach to regenerate tissues and organs. Guiding principles for proper selection of three basic components for tissue engineering: cells, scaffolds, and molecular signals. Concurrently scheduled with course C285. Letter grading. Mr. Wu (Sp)

M196A. Introduction to Cybernetics, Biomodeling, and Biomedical Computing. (2) (Same as Computer Science M196A and Cybernetics M196A.) Lecture, two hours. Requisites: Mathematics 31A, 31B, Program in Computing 10A. Strongly recommended for students with potential interest in biomedical engineering/biocomputing fields or in Cybernetics as a major. Introduction and survey of topics in cybernetics, biomodeling, biocomputing, and related bioengineering disciplines. Lectures presented by faculty currently performing research in one of the areas; some sessions include laboratory tours. P/NP grading. Mr. DiStefano (W)

M196B. Computational Systems Biology: Modeling and Simulation of Biological Systems. (5) (Same as Computer Science M196B, Cybernetics M196B, and Medicine M196B.) Lecture, four hours; discussion, one hour; laboratory, two hours. Requisite: Electrical Engineering 102 or Mathematics 115A. Introduction to dynamic system modeling, compartmental modeling, and computer simulation methods for studying biomedical systems. Basics of numerical simulation algorithms, translating biomodeling goals and data into mathematic models and implementing them for simulation and analysis. Modeling software exploited for class assignments in PC laboratory. Letter grading. Mr. DiStefano

CM196L. Biomedical Systems/Biocybernetics Research Laboratory. (2 to 4) (Same as Computer Science CM196L and Cybernetics M196L.) Lecture, two hours; laboratory, two hours. Requisite: course M196B. Special laboratory techniques and experience in biocybernetics research. Laboratory instruments, their use, design, and/or modification for research in life sciences. Special research hardware, firmware, software. Use of simulation in experimental laboratory. Laboratory automation and safety. Comprehensive experiment design. Radioactive isotopes and kinetic studies. Experimental animals, controls. Concurrently scheduled with course CM296L. Letter grading. Mr. DiStefano

2002-2003